objective: diabetes mellitus is one of the most common endocrine diseases with micro-vascular complications and is a common cause of polyneuropathy. we studied the effect of enalapril on electrophysiologic criteria and clinical symptoms of patients with type ii diabetes and sensory neuropathy. materials and methods: a double blind study was conducted on 45 patients with type ii diabetes and neu...

background: diabetic peripheral neuropathy (dpn) accounts for 80% of diabetic foot ulceration; therefore neurologic examination plays a critical role in screening at risk patients. our objective was assessment the prevalence of dpn and related factors based on clinical findings. methods: this cross-sectional study was conducted on 124 diabetics who were randomly recruited from diabetes clinic o...

clinical assessment of distal symmetric polyneuropathy (dpn) involves the evaluation of symptoms and signs. although there are numerous tools to evaluate dpn, there is still a need to determine the most sensitive, specific, and accurate tests to detect dpn in a busy outpatient clinical setting. a total of 107 patients with type 2 diabetes were examined using michigan neuropathy screening instru...

conclusions both tens and prf lumbar sympathectomy are promising pain relief treatments for painful dnp. however, prf lumbar sympathectomy seems to have a superior efficacy. further studies with a larger sample size and a longer follow-up period are needed. background painful diabetic peripheral neuropathy (dpn) is a long-term complication of type 1 and type 2 diabetes that majorly impacts qual...

objective(s):painful diabetic neuropathy is associated with hyperexcitability and hyperactivity of spinal cord neurons. however, its underlying pathophysiological mechanisms have not been fully clarified. induction of excitatory/inhibitory neurotransmission imbalance at the spinal cord seems to account for the abnormal neuronal activity in diabetes. protective properties of neurosteroids have b...

abstract background: diabetic neuropathy is the most common micro-vascular complications of diabetes. the drugs including gabapentin and duloxetine are often used for the treatment of pain associated with diabetic neuropathy. this study aimed to compare the efficacy of duloxetine and gabapentin in the treatment of diabetic peripheral neuropathy. materials and methods: totally, 34 patients aged ...